Post Doctoral Fellow - Internal Medicine (Endocrinology, Diabetes, & Clinical Pharmacology)

University of Kansas Medical Center Kansas City, KS Full-time Health Care Provider

Posted on May 15, 2024

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Post Doctoral Fellow - Internal Medicine (Endocrinology, Diabetes, & Clinical Pharmacology)

Department:
SOM KC Internal Medicine - Endocrinology, Metabolism & Genetics
-----
Diabetes Institute

Position Title:
Post Doctoral Fellow - Internal Medicine (Endocrinology, Diabetes, & Clinical Pharmacology)

Job Family Group:
Professional Staff

Job Description Summary:
A postdoctoral position is available in the laboratory of Andrew Lutkewitte, Assistant Professor in the Division of Endocrinology, Diabetes, and Clinical Pharmacology. Our research program seeks to increase our understanding of metabolic crosstalk between tissues in the context of obesity. This specific project aims to establish the mechanistic links between adipose tissue dysfunction and dysregulated hepatic metabolism. This project will use comprehensive metabolic testing combined with multi-omic approaches to assess the signaling mechanisms that drive hepatic de novo lipogenesis following adipose dysfunction. We have established several mouse models of adipose tissue dysfunction and loss; in addition, we use several in vitro cell lines and primary hepatocytes and adipocytes to study the molecular mechanism in controlled conditions using radio and isotopic tracing methods. Additional projects in the lab include identifying molecular mechanisms controlling adipose tissue triglyceride synthesis. If interested, please send a letter describing your research experience/interest/future career aspirations, CV, and contact information for three references.

Postdoctoral scholars at the University of Kansas Medical Center are individuals who have received their terminal degree and who have opted to pursue further training in a postdoctoral appointment. Postdoctoral scholarship is a time-limited appointment, the primary purpose of which is to provide research and/or scholarly training for an academic or research career.

Job Description:

Required Qualifications

Education: Ph.D. or equivalent in the field of metabolism with 4 years of research experience

Work Experience: Prior experience with human/mouse biospecimen processing, animal husbandry and colony management and cell culture.

Skills:

Must have the ability to plan, organize, and work as part of an interactive team.
Experimental design, implementation, and analysis. General research methods include pipetting, centrifugation, and reagent handling.

Preferred Qualifications

Skills:

Proficiency with routine biochemical techniques, molecular biology, immunohistochemistry, sterile cell culture, DNA, RNA and protein-based assays. Additionally, experience in animal handling and metabolic analysis, dissection, and downstream tissue analyses. Finally, experience working with mouse models of metabolic disease.
Demonstrated ability to run multiple independent projects and competing priorities simultaneously.
Need to have good communication skills and prepare presentations for lab meetings and local conferences.
Experience with analysis of large data sets include RNA seq and Proteomics.

Job Duties

Lead projects related to adipose tissue-liver crosstalk using multiple mouse models.
Perform experiments using cell culture to understand mechanisms underlying obesity-related metabolic disease. Experiments will involve primary cell culture, biochemistry, molecular biology assays, techniques such as immunoblotting, and qPCR etc.
Perform experiments independently and as a team using animal models of obesity and fatty-liver disease.
Metabolic assessment of animal models using indirect calorimetry, BioDaq food intake monitoring system, Echo MRI, and other methods such as insulin/glucose tolerance testing.
Facilitate studies using adeno-associated viral expression of metabolic genes in vivo.
Isolation of primary cells from mouse tissues (adipose, liver).
Design new experimental plan independently in consultation with the supervisor.
Apply for postdoctoral research grants/ travel awards.
Attend and present at weekly research and study team meetings as well as national/international meetings.

Required Documents

Resume/CV
Cover letter

Comprehensive Benefits Package:

Coverage begins on day one for health, dental, and vision insurance and includes health expense accounts with generous employer contributions if the employee participates in a qualifying health plan. Employer-paid life insurance, long-term disability insurance, and various additional voluntary insurance plans are available. Paid time off, including vacation and sick, begins accruing upon hire, plus ten paid holidays. One paid discretionary day is available after six months of employment, and paid time off for bereavement, jury duty, military service, and parental leave is available after 12 months of employment. A retirement program with a generous employer contribution and additional voluntary retirement programs (457 or 403b) are available. https://www.kumc.edu/human-resources/benefits.html

Employee Type:
Regular

Time Type:
Full time

Rate Type:
Salary

Compensation Statement:

The pay range listed for this position is determined by our compensation program using market data and salary benchmarking. A combination of factors is considered in making compensation decisions including, but not limited to, education, experience and training, qualifications relative to the requirements of the position, and funding. At the University of Kansas Medical Center, a reasonable estimate for the starting pay range will be the minimum to midpoint of the posted range, taking into account the combination of factors listed above.

Pay Range:
$47,476.00 - $80,000.00
Minimum
$47,476.00
Midpoint
$66,000.00
Maximum
$80,000.00

Application Instructions:
To learn more and apply online, please visit https://kumc.wd5.myworkdayjobs.com/en-US/kumc-jobs/job/Kansas-City-Metro-Area/Post-Doctoral-Fellow---Internal-Medicine--Endocrinology--Diabetes----Clinical-Pharmacology-_JR007008 or go to https://careers.kumc.edu/ and search for position number JR007008.

Applications must be submitted directly through the KU Medical Center website to be considered for this position. Any applications submitted via email or this website will NOT be reviewed or considered.

About KU Medical Center:
The University of Kansas Medical Center’s mission is to educate exceptional health care professionals through a full range of undergraduate, graduate, professional, postdoctoral and continuing education programs in the schools of Medicine, Nursing and Health Professions. KU Medical Center also advances the health sciences through world-class research programs; provides compassionate and state-of-the-art patient care in an academic medical center environment; and works with communities in every Kansas county to improve the health of Kansans. Learn more at www.kumc.edu.

Benefits:
KUMC offers a range of great benefits that support employees and eligible family members. Our health insurance benefits begin on hire date and KUMC offers other exciting benefits such as paid parental leave, generous employer retirement contributions and other resources to improve health and well-being. For more information, please visit https://www.kumc.edu/human-resources/benefits.html

Equal Employment Opportunity Statement

The University of Kansas Medical Center is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, ethnicity, ancestry, age, protected veteran or disability status, marital status, parental status, or genetic information. http://policy.ku.edu/IOA/nondiscrimination

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